The following lists contain some of the key side effects that may occur while taking Zetia. Zetia can be used to treat high cholesterol or homozygous sitosterolemia (a condition that causes high fat levels) in certain people. Zetia may also increase the amount of cholesterol thats stored in your gallbladder. An allergic reaction is possible after using Zetia. Using Zetia for high cholesterol. Cholesterol is made naturally in your liver. In the video she posted on Thursday, the "Real Housewives of New York City" alum detailed her suffering from a severe dehydration issue and shared that her doctor . At the end of the study, researchers found that: Mixed hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol and fats are cleared from your body. Zetia does not cause an increase or a decrease in blood pressure. They can recommend treatments that may help with joint pain, or they may recommend a different treatment option for you. More common side effects in people taking Zetia* include: * In studies, these side effects were reported in people who took Zetia by itself. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Note: Some of the drugs listed here are used off-label to treat these specific conditions. It belongs to a class of drugs called cholesterol absorption inhibitors. If youre using Zetia while sexually active with a female who could become pregnant, talk with your doctor about your birth control needs. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. A life-changing condition called POTS, which can cause fainting, irregular heartbeats and dizziness, particularly among young women, appears to be on the rise as a result of the coronavirus pandemic. Each type is described below in more detail. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. POTS is a kind of dysautonomia or autonomic nervous disorder. Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. They can suggest ways to help relieve this side effect. In fact, researchers have looked into using Zetia to treat hair loss due to a condition called alopecia areata. Zetia and Crestor are both brand-name drugs. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. Currently, no medications have been approved by the FDA to treat POTS. Or should I wait to see if I develop such side effects? The cause of the disorder is unknown. Zetia contains the active drug ezetimibe. . Do not use more Zetia than your doctor recommends. Zetia is a brand-name prescription drug. It can develop suddenly or gradually over time. Yes, there are a few. This section doesnt contain all drugs that may interact with Zetia. These drugs havent been directly compared in clinical studies. Grapefruit can prevent the breakdown of these drugs in your body. Zetia may be used with statin drugs or with fenofibrate when used to treat certain conditions. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Or they may recommend a product you apply to your skin, such as hydrocortisone cream. You may wonder how Zetia compares with other medications that are prescribed for similar uses. Clinical studies involved adults and children ages 10 years and older. * To learn more about this side effect, see the Side effects explained section below. Effects of coenzyme Q10 on statin-induced myopathy: An updated meta-analysis of randomized controlled trials. Many rare diseases have limited information. Zetia is a casebook example of the role the pharmaceutical industry increasingly chooses to play as it intervenes in human lives for corporate profit. Therefore, you shouldnt breastfeed if youre taking Zetia with a statin drug. Theyll guide you on the safest treatment options for you. Cardiology 33 years experience. Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health . Learn about the drugs dosage, forms, strengths. But its possible that some side effects may continue to affect you for as long as youre taking the medication. 2. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. If youre taking Zetia, talk with your doctor or pharmacist to see whether CoQ10 could be a good supplement for you. However, its important that you dont stop taking Zetia without first talking with your doctor. For instance, some interactions can interfere with how well a drug works. Also, tell your doctor right away if you become pregnant while taking this drug. Your doctor may prescribe Zetia with a statin drug. Zetia can cause the breakdown of muscle tissue, which can lead to kidney failure. Zetia and Lipitor have some similar side effects and others that vary. Most of Zetias side effects should go away within a few days or weeks. However, be sure to take the dosage your doctor prescribes for you. The symptoms develop immediately and include dizziness and an intense headache. This helps prevent others, including children and pets, from taking the drug by accident. If you already have liver problems, taking Zetia may worsen your condition. As a result, it's critical to drink lots of fluid throughout the day to keep your hydration levels up. 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. They can both be taken with or without food. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Crossing your legs in front of each other while standing, rocking up and down on your toes. What are the more common side effects of Zetia? Postural orthostatic tachycardia syndrome (POTS) is a condition that causes a number of symptoms when you transition from lying down to standing up, such as a fast heart rate, dizziness and fatigue. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. Statins are commonly prescribed with Zetia to treat certain types of high cholesterol. You may not have any symptoms of gallstones unless they cause your gallbladder to swell. Porphyria patients are often overly sensitive to sunlight. Can diet help improve depression symptoms? People with HoFH have high levels of LDL (bad) cholesterol. They can give you tips on how to deal with any side effects that may be bothersome. Avoid eating foods high in fat or cholesterol, or Zetia will not be as effective. Zetia may cause joint pain. Zetia isnt known to interact with grapefruit or any other foods. Zetia is FDA-approved to treat mixed high cholesterol when used with fenofibrate. Youll likely take it once a day. The dosage is the same for all approved uses. Currently GARD aims to provide the following information for this disease: Population Estimate: This section is currently in development. . Since every POTS patient is different, some may primarily experience gastrointestinal symptoms, such as nausea, vomiting or poor feeding, Berger explained. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. No, clinical studies havent shown Zetia to affect blood pressure. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. If you drink alcohol and have questions about drinking it during Zetia treatment, talk with your doctor. Zetia contains the active drug ezetimibe. If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. If you drink alcohol, talk with your doctor about whether its safe for you to drink during your Zetia treatment. Some people may develop mild or serious side effects during Zetia treatment. Examples of bile acid sequestrants include: Zetia inhibits the intestinal absorption of cholesterol and phytosterols, resulting in a decrease in the transport of intestinal cholesterol to the liver. Qu H, et al. For more information on possible side effects of Zetia, see the Zetia side effects section above. Its not known if Zetia is safe to take during pregnancy. Some side effects are more common than others. Ezetimibe may cause side effects. Zetia (ezetimibe) is a prescription drug that treats high cholesterol in adults and children. Lying down on the bed, and raising your legs. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Statin drugs may pass into breast milk. Lipitor is available in a generic form called atorvastatin. This disorder affects the autonomic nervous system, which controls involuntary body functions such as body temperature and heart rate. Specific conditions, or they may recommend a product you apply to your skin, such as body and... While taking Zetia may also increase the amount of cholesterol thats stored in your body any weight loss may! To play as it intervenes in human lives for corporate profit since starting Zetia, this may used! Casebook example of the role the pharmaceutical industry increasingly chooses to play it... 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